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  1. 13 de ago. de 2021 · Numerous drugs are capable of triggering the rare idiosyncratic form of agranulocytosis, which, unlike agranulocytosis induced by cytotoxic drugs in cancer chemotherapy, is characterised by “bizzare” type B or hypersensitivity reactions, poor predictability and a mainly low incidence.

  2. 21 de sept. de 2022 · Drug-induced neutropenia and agranulocytosis will be reviewed here. Others causes of acquired neutropenia, such as primary immune mechanisms, chemotherapy, and infections, as well as congenital neutropenia in children are discussed separately.

  3. 23 de may. de 2023 · The diagnosis of agranulocytosis requires a high degree of suspicion based on signs and symptoms, medication use, recent exposure to chemical agents, and infections. A complete blood count (CBC) with the differential count is used in the initial workup.

  4. 4 de feb. de 2017 · Idiosyncratic drug-induced agranulocytosis (IDIA) or acute severe neutropenia is historically characterized by neutrophil count ≤0.5 × 10 9 /L, impaired health and severe mucositis. 1 IDIA is a relatively rare disorder, has an annual incidence of 2–15 cases per million. 2 Whilst all drugs can be considered cause of IDIA, cotrimoxazole ...

  5. Drug-induced agranulocytosis is a rare, potentially fatal idiosyncratic reaction that can occur unpredictably with a wide variety of drugs when taken in a conventional dose. In this article, we discuss its diagnosis and management and we consider the drugs most commonly involved and ways of minimising risk.

  6. 28 de ene. de 2024 · Most drugs that cause adverse events are difficult to identify in critically ill patients undergoing polypharmacy. We share our experience in identifying the causative drug among four suspect drugs administered during emergency treatment. Abstract. agranulocytosis, clopidogrel, elobixibat, Hange‐Koboku‐Toh, lansoprazole, multiple drug use. Go to:

  7. 8 de dic. de 2017 · Patients typically experience acute, severe neutropenia, or agranulocytosis (<0.5 × 10 9 neutrophils/L) and symptoms of fever, chills, sore throat, and muscle and joint pain. Diagnosis can be difficult, but timely recognition is critical because if left untreated, there is an increase in mortality.