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29 de feb. de 2024 · The enormous potential of recombinant DNA technology was first envisioned by Stanford biochemistry graduate student Peter Lobban., Assuming cells containing cloned genes could express their new genetic information, Lobban proposed they could be used to manufacture therapeutically important proteins.
Paul Naim Berg (Nueva York, 30 de junio de 1926-Stanford, 15 de febrero de 2023) [1] fue un bioquímico y profesor estadounidense en la Universidad de Stanford (en California). Recibió el Premio Nobel de Química en 1980, junto con Walter Gilbert y Frederick Sanger.
1 de ene. de 2010 · In his proposal and Ph.D. thesis (Lobban 1972, Lobban) foresaw the prospect of inserting any foreign DNA, including from mammalian cells, into the phage DNA.
Historians of science, however, have pointedly noted that experimental procedures for making recombinant DNA molecules were initially developed by Stanford biochemist Paul Berg and his colleagues, Peter Lobban and A. Dale Kaiser in the early 1970s.
La historia comienza en 1972, cuando se encontró la ligasa, la enzima que permite pegar genes, con lo que Paul Berg y Peter Lobban, ese mismo año, de forma independiente, obtuvieron la primera molécula de ADN recombinante, con la unión de trozos de ADN de especies diferentes.
initially developed by Stanford biochemist Paul Berg and his colleagues, Peter Lobban and A. Dale Kaiser, in the late 1960s and early 1970s.3 More interestingly, Lobban was often seen by fellow scientists as one of the scientists who first recognized the potential use of recombinant DNA technology for genetic engineering in 1969, a few years before
16 de sept. de 2013 · The procedure is robust, and Peter Lobban, a graduate student working with A. Dale Kaiser in the Stanford Department of Biochemistry, had begun using it to introduce phage P22 DNA into Salmonella typhimurium, a close relative of E. coli.
