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La secuenciación de células individuales (single-cell sequencing en inglés) es un conjunto de tecnologías utilizadas para determinar el orden de los nucleótidos en el ADN o ARN de células individuales.
Single-cell RNA sequencing was performed on cells isolated from milk and blood of three Holstein cows with chronic mastitis caused by experimental Staphylococcus aureus infection. Cells were classified into 62 clusters and annotated as 6 different cell types.
31 de mar. de 2023 · Recent advances in single-cell technologies have enabled high-throughput molecular profiling of cells across modalities and locations. Single-cell transcriptomics data can now be...
6 de jun. de 2023 · Single-cell multi-omics technologies and methods characterize cell states and activities by simultaneously integrating various single-modality omics methods that profile the transcriptome,...
6 de nov. de 2015 · The key to single-cell biology, of course, is isolating a single cell. This typically is accomplished using micromanipulation, microfluidics, or fluorescence-activated cell sorting (FACS), the method Stepanauskas favors.
19 de abr. de 2024 · Here, we construct a single-cell multi-omics map of human tissues through in-depth characterizations of datasets from five single-cell omics, spatial transcriptomics, and two bulk omics across 125 healthy adult and fetal tissues.
2 de feb. de 2023 · Single-cell analysis has led to the discovery of new cellular phenomena and enabled the investigation of disease microenvironments, thereby identifying new cellular and molecular targets for the diagnosis and treatment of refractory diseases.
