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23 de feb. de 2021 · Concerns with endotoxin risks in relation to reverse osmosis are central to a new European Medicines Agency guidance paper relating to pharmaceutical water production. This article considers the key messages within the guidance and the important learning points in relation to contamination control.
The final rinse water should be free of bacteria and is an essential step in decontamination because it removes traces of disinfectants which could otherwise be hazardous to patients and staff.
Background: The penultimate stage in endoscope reprocessing is the final rinse with water following terminal disinfection. This requires a degree of microbiological and chemical control of the quality of the final rinse water.
170 should also be used for the final rinse after the cleaning of equipment and components that
Water of impeccable microbiological quality must be used for the final rinse when cleaning and disinfecting endoscopes in the EWD as well as for manual cleaning and disinfection in order to prevent endoscope recontamination.
1. INTRODUCTION. Water is one of the major commodities used by the pharmaceutical industry. It may be present as an excipient, or used for reconstitution of products, during synthesis, during production of the finished product or as a cleaning agent for rinsing vessels, equipment, primary packaging materials etc.
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