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Hace 3 días · However, a bacterial cytological profiling showed a different pattern for SCH-79797 than for trimethoprim, a known folate antagonist antibiotic, suggesting a distinct MoA. Flow cytometry with fluorescent dyes demonstrated that SCH-79797 disrupted both the membrane potential and permeability barrier.
Hace 2 días · The chemotactic ability of microbial populations has recently been measured directly in the ocean using a new approach, the in situ chemotaxis assay (ISCA), a field-based microfluidic platform that generates diffusive point sources of chemicals and allows for selective capture of live bacteria from the environment as a result of their ...
Hace 1 día · Monoclonal antibodies (mAbs) target bacterial virulence factors, aiding in bacterial destruction through various mechanisms. Three FDA-approved antibodies target B. anthracis and C. difficile toxins.
26 de jun. de 2024 · Methicillin-resistant Staphylococcus aureus (MRSA) is one of the leading causes of mortality due to bacterial antimicrobial resistance. While S. aureus is common in skin and soft tissue infections (SSTI) in Afric...
Hace 4 días · In most bacteria, resistance can be through three different mechanisms – reduced permeability in bacteria, reduced binding affinity of the penicillin-binding proteins (PBPs) or destruction of the antibiotic through the expression of β-lactamase.
Hace 4 días · In this study, a novel bio-composite material that allow sustained release of plant derived antimicrobial compound was developed for the biomedical applications to prevent the infections caused by microorganisms resistant to commercial antimicrobials agents.
Hace 5 días · AMPs, secreted from the epithelial surface of various species, have a relatively short amino acid structure and exhibit direct and indirect antimicrobial activity against various infectious agents. Apart from directly eliminating bacteria, AMPs exhibit immunomodulatory activity .
