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UFT – UFT is a 1:4 molar combination of the FU prodrug ftorafur (Tegafur) with uracil (which competitively inhibits the degradation … Adjuvant therapy for resected stage III (node-positive) colon cancer
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OBJECTIVE Various forms of neoadjuvant chemotherapy (NAC) have been applied in the treatment of gastric cancer. The present study was designed to assess the survival benefits of NAC with UFT (tegafur plus uracil) for gastric cancer, as a randomized consent trial as described by Zelen.
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PURPOSE The primary aim of this study was to compare the relative efficacy of oral uracil and tegafur (UFT) plus leucovorin (LV) with the efficacy of weekly intravenous fluorouracil (FU) plus LV in prolonging disease-free survival (DFS) and overall survival (OS) after primary surgery for colon carcinoma.
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