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24 de jun. de 2024 · Candidate peak-gene pairs are then identified by first associating peaks within a genomic distance of 250kb to the TSS of each gene, and then computing the Pearson correlation coefficient of the log 2 normalized accessibility and gene expression counts.
Hace 4 días · The Pearson χ 2 test was used to test the overlap between established gene-expression endotypes and latent profile phenotypes. Kaplan Meier curves were used to estimate differences in survival comparing endotypes, phenotypes, and an integrated subclass assignment scheme where we considered outputs of both these approaches.
Hace 3 días · Gene significance (GS) was defined as the absolute value of the correlation between external traits and gene expression profiles. Subsequently, modules significantly associated with advanced or ruptured plaques, and exhibiting a significant correlation between MM and GS values (with an absolute correlation coefficient greater than 0.3), were ...
Hace 3 días · The concept of gene expression plasticity and evolutionary fixation is fundamental to understanding how cell populations adapt to rapid environmental changes in a growing tumor. ... f Pearson correlation between clonal proportions in DLP, and inferred clonal proportions in 10x – scRNA-seq expression at the same passages from patient Pt4 using ...
Hace 2 días · Carucci, J. A. et al. Calcitonin gene-related peptide decreases expression of HLA-DR and CD86 by human dendritic cells and dampens dendritic cell-driven T cell-proliferative responses via the type ...
12 de jul. de 2024 · The test statistic used was Pearson’s product moment correlation coefficient. Kaplan-Meier curves were generated using “survival” R package . Patients were grouped into low, medium, high, and top expression quartiles based on the expression level of the specific gene. ... The gene expression values were log 2-transformed, and the model ...
Hace 4 días · SAP is encoded by the gene APCS (ENSG00000132703) located on chromosome 1, ... the Pearson correlation coefficient comparing the −log 10 (p-value) for each trait was −0.06, p-value < 0.001. This was further confirmed by noting that the CRP association of the four SAP cis-variants did not reach genome-wide significance ...
