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In this article, we critically review the epidemiology, pathogenesis, diagnosis, and presentation of drug-induced pancreatitis. We also discuss drugs and classes of drugs strongly implicated in mediating or modulating acute pancreatitis based on well-documented case reports and laboratory investigation. 3, 4.
- Drug induced pancreatitis: A systematic review of case reports to ...
Seven-hundred and thirteen cases of potential drug-induced...
- Drug-Induced Acute Pancreatitis in Adults: Focus on Antimicrobial and ...
Acute pancreatitis (AP) is an acute inflammation of the...
- Drug-induced pancreatitis: an update - PubMed
Medications implicated in AP are classified based on the...
- Drug induced pancreatitis: A systematic review of case reports to ...
17 de abr. de 2020 · Seven-hundred and thirteen cases of potential drug-induced pancreatitis were identified, implicating 213 unique drugs.
29 de sept. de 2023 · Acute pancreatitis (AP) is an acute inflammation of the pancreas caused by the activation of digestive enzymes in the pancreatic tissue. The main causes of AP are cholelithiasis and alcohol abuse; less commonly, it can be caused by drugs, with a prevalence of up to 5%.
Medications implicated in AP are classified based on the strength of evidence into one of three classes of drugs associated with pancreatitis. We reviewed the top 100 prescription medications in the United States for their association with AP.
Only 3 drugs had evidence as causing acute pancreatitis from randomized controlled clinical trials, including 6-mercaptopurine and azathioprine (class 1). Only 14 drugs were shown from case-control trials or pharmacoepidemiologic studies as causing acute pancreatitis (class 2).
More than 100 drugs have been implicated as the cause of acute pancreatitis and different mechanisms of injury have been proposed. The last collective report of DIAP was in 2007 published by Badalov et al. The aim of our study was to include the new cases in the past 10 years.
This article reviews the advances in the incidence, risk factors, pathogenesis, diagnosis, treatment and prevention of drug-induced pancreatitis by reviewing the literature on drug-induced pancreatitis, especially in the literature of the latest 10 years.
