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1 de nov. de 2002 · Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA Jordan S. Orange, Marlys S. Fassett, Louise A. Koopman, Jonathan E. Boyson & Jack L. Strominger
3 de ago. de 2007 · The characteristic covalent labeling of these enzymes by the -lactams, first observed by Strominger [4], is acknowledged in the continued use of " penicillin binding protein " (PBP) to describe ...
HLA-G Antigens. Isoantigens. During pregnancy, semiallogeneic fetal extravillous trophoblasts (EVT) invade the uterine mucosa without being rejected by the maternal immune system. Several mechanisms were initially proposed by Peter Medawar half a century ago to explain this apparent violation of the laws of transplantation. The ….
The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation. DR Madden, JC Gorga, JL Strominger, DC Wiley. Nature 353 (6342), 321-325. , 1991. 917. 1991. The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC.
Natural killer (NK) cells comprise a subset of lymphocytes involved in protection against microbial pathogens and tumors. NK cells recognize host cells that are missing MHC class I molecules and eliminate them through localized delivery of lytic granules. The majority of NK cell effector functions require direct cell-to-cell contact.
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MICROBIAL I. BIOLOGY URIDINE-5'-PYROPHOSPHATE SUGAR COMPOUNDS OF THE PENICILLIN-INDUCED L. STROMINGERt N-ACETYLAMINO ACCUMULATION* BY JACK (From the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Bethesda, &.faryland) (Received for publication, April 17, 1956) The observation of Park and Johnson (1) that uracil-containing compounds accumulate in ...
